Veterinary Medicine Colistin Sulphate with GMP for Animal Antibiotics
Specification: Pure, 10% Premix
Characteristics:
Pure: White or yellowish powder; Odorless or almost odorless; hygroscopicity; soluble in water, slightly soluble in ethanol, practically insoluble in acetone.
CAS NO.: 1264-72-8
Pharmacology:
Chronic fungicides. A free amino group with positive charge of Colistin can combine with phosphate (with negative charge) of phospholipid which in the membrane of gram-negative bacilli. This will make membrane surface expanded and perneability increased, intracellular phosphate, nucleotides and other
components leaked, leading to cell death. Mainly have a strong antibacterial effect on gram-negative bacteria, susceptible strains are E. coli, Enterobacter, Salmonella, Shigella, Proteus, Klebsiella, Pasteur's bacteria, Vibrio etc.
Indications:
Antibiotic, used to treat gastro-intestinal diseases caused by gram-negative
bacteria. Also has certain growth-promoting effect.
Advantages:
- It has strong anti-bacteria activity against Gram-negative bacteria.
- Low incidence of anti-drug reactions.
- No drug cross-resistance with other antibiotics.
- It cannot be particularly absorbed in alimentary tract. It is highly safe and in lack of residue. It is especially manufactured for healthy foods.
- It promotes growth and increases feed utilization rate.
Usage&Dosage:
Mixed feeding. Recommended Dosage:
| Animal Species |
Colistin Sulphate 10% Premix
(g) per 1000 kg feeding stuff |
Colistin Sulfate Concentration
(ppm) |
| Broiler Chicken |
20-200 |
2-20 |
| Cattle |
50-400 |
5-40 |
Pig
(breast-feeding period ) |
20-400 |
2-40 |
Pig
(piglet period) |
20-200 |
2-20 |
Pig
(fattening period) |
40-400 |
4-40 |
Precautions:
Forbid using in the laying chicken. No other untoward effects.
Withdrawal Period: 7 days.
Package:
Pure: 20 kg/drum
Premix: 25 kg/bag.
Storage: Store in a cool and dry place, in sealed or closed container.
Expiry Date: Two years.
